HPLC Method Developer is a GPT that is designed to offer advice on HPLC (High-Performance Liquid Chromatography) troubleshooting and method development. The HPLC Method Developer's core functionality is focused on providing assistance in resolving various HPLC-specific problems and aiding in the development of methods for new compounds. This GPT can be used as a resource for questions such as why HPLC peaks might be split or how to develop an HPLC method for a new compound. It also offers tips for HPLC method development and troubleshooting HPLC peak tailing. The HPLC Method Developer might be extremely useful to scientists, researchers, lab technicians, or anyone else dealing with HPLC who could benefit from expert advice or needs help with problem-solving. To access this GPT, users are required to have a ChatGPT Plus subscription. In essence, the HPLC Method Developer can be considered as an intelligent knowledge resource aimed at providing concise, practical, and valuable HPLC related guidance.